Comedoclastin^TM

Comedoclastin^TM, a new ingredient with patented properties derived from Pierre Fabre's expertise

After 8 years of research and development to extract the most active component of the plant, Laboratoires Dermatologues Avène have produced Comedoclastin^TM from the seeds of Milk Thistle (Sylibum marianium L.). Pierre Fabre Botanical Expertise has obtained the active molecules and stabilised them to obtain a unique concentrate, an oil rich in active ingredients extracted from cold-pressed seeds in our ISO9100 certified factory in Gaillac, which guarantees traceability, safety and control of the manufacturing process. 

Predominantly grown in France in a short supply chain within a non-destructive industry, milk thistle extract meets the four founding pillars of the Pierre Fabre Botanical Expertise approach, a certified responsible development approach that consists of innovating through nature: to help fight against the depletion of plant resources and contribute to their preservation, while guaranteeing the extreme quality of active plant ingredients, the security of supplies and respecting our partners* *https://www.pierre-fabre.com/en/our-group/our-commitments/protecting-biodiversity

And in a circular economy context, the residual oil of milk thistle obtained after extraction is also recovered.

Comedoclastin^TM is an effective part of our Cleanance Comedomed skin care range.

We have applied the effectiveness of our star ingredient Comedoclastin^TMto our entireCleanance Comedomedskin care range to care for oily or blemish-prone skin in two ways:

• In a hyper-concentrated form, with a 25% concentration of Cleanance Comedomed Anti-Blemish Concentrate, a product that reduces the appearance of blemishes and blackheads while limiting their recurrence to leave your skin looking clear. 
• Combined with other ingredients across other products in the range such as Cleanance Gel, a mattifying gel cleanser that removes oil and impurities for perfectly cleansed and matte skin.